Wednesday, March 2, 2011
Fine scale analysis of Eurogenes' Anatolian & European Turks
This is a supervised run with the new ADMIXTURE 1.1, featuring project members from all over Turkey. What does "supervised" mean? It means that the origins of the reference samples have already been flagged by me, and the program then works to match the test samples to these references.
I didn't use a Turkish reference set on purpose, because I already knew that the test samples were Turks, and wanted to see what kind of near and far populations potentially contributed to the modern Anatolian gene pool. But I did include reference Uzbeks and Uygurs for comparison, and it's fascinating to note the high "Central-Eastern European" in these samples. These results were obtained with Hungarians and Romanians as proxies for that component, but other samples from the region, like Poles, work just as well.
Key: Red = Armenian + Georgian (Anatolian & Caucasus), Orange = Cypriot + Greek (Southeastern European), Light Green = North Kannadi + Sakilli + Selected Gujarati (South Asian), Green = Hungarian + Romanian (Central-Eastern European), Aqua = Han Chinese (East Asian), Blue = Iranian, Dark Blue = Mandenka + Bantu (Sub-Saharan African), Purple = Palestinian + Saudi Arabian (Arabian), Pink = Evenk + Nganassan + Yakut (Siberian). See spreadsheet for details.
Update: I'm getting a lot of comments in a forum discussion about the variable spread of some of these components in the test samples. It's really difficult to answer why one Turkish sample might show 0% membership in a cluster, while another more than 20%. But I just ran an MDS of various sets to see whether some of these patterns could be reproduced visually, and yes they can. Note that TR3, who comes out 100% red (Armenian + Georgian), clusters with Armenians and Georgians on these plots. On the other hand, TR10, shows no blue (Iranian) in the ADMIXTURE analysis, and backs that up with her behavior on the MDS plots, by pulling away form the Iranians towards the Uzbeks on one plot, and Pathans on another.